What is the best Content Management System ?

I guess the title says pretty much that’s it. What I meant by "best" is easier to use and flexible to change the layout without actually digging up into CSS.

You pick…

Free Content Management Systems:

http://www.pligg.com/

http://drupal.org/

http://opensourcecms.com/

http://www.joomla.org/

http://www.opensourcecms.com/

File Thingie?(small web-based file manager written in PHP. It is intended for those who need to give others access to a part of their server’s file system when FTP is not practical): http://www.solitude.dk/filethingie/

Ron